Large outbreaks of Shigella sonnei among children in Haredi Jewish (ultra-Orthodox) communities in Brooklyn, New York have occurred every 3–5 years since at least the mid-1980s. These outbreaks are partially attributable to large numbers of young children in these communities, with transmission highest in child care and school settings, and secondary transmission within households. As these outbreaks have been prolonged and difficult to control, we developed an agent-based model of shigellosis transmission among children in these communities to support New York City Department of Health and Mental Hygiene staff. Simulated children were assigned an initial susceptible, infectious, or recovered (immune) status and interacted and moved between their home, child care program or school, and a community site. We calibrated the model according to observed case counts as reported to the Health Department. Our goal was to better understand the efficacy of existing interventions and whether limited outreach resources could be focused more effectively.

This package implements a simplified artificial agent-based demographic model of the UK. Individuals of an initial population are subject to ageing, deaths, births, divorces and marriages. A specific case-study simulation is progressed with a user-defined simulation fixed step size on a hourly, daily, weekly, monthly basis or even an arbitrary user-defined clock rate. While the model can serve as a base model to be adjusted to realistic large-scale socio-economics, pandemics or social interactions-based studies mainly within a demographic context, the main purpose of the model is to explore and exploit capabilities of the state-of-the-art Agents.jl Julia package as well as other ecosystem of Julia packages like GlobalSensitivity.jl. Code includes examples for evaluating global sensitivity analysis using Morris and Sobol methods and local sensitivity analysis using OFAT and OAT methods. Multi-threaded parallelization is enabled for improved runtime performance.

This model simulations social and childcare provision in the UK. Agents within simulated households can decide to provide for informal care, or pay for private care, for their loved ones after they have provided for childcare needs. Agents base these decisions on factors including their own health, employment status, financial resources, relationship to the individual in need and geographical location. This model extends our previous simulations of social care by simulating the impact of childcare demand on social care availability within households, which is known to be a significant constraint on informal care provision.

Results show that our model replicates realistic patterns of social and child care provision, suggesting that this framework can be a valuable aid to policy-making in this area.