Identifying how organisms respond to environmental stressors remains of central importance as human impacts continue to shift the environmental conditions for countless species. Some mammals are able to mitigate these environmental stressors at the cellular level, but the mechanisms by which cells are able to do this and how these strategies vary among species is not well understood. At the cellular level, it is difficult to identify the temporal dynamics of the system through empirical data because fine-grained time course samples are both incomplete and limited by available resources. To help identify the mechanisms by which animal cells mitigate extreme environmental conditions, we propose an agent-based model to capture the dynamics of the system. In the model, agents are regulatory elements and genes, and are able to impact the behaviors of each other. Rather than imposing rules for these interactions among agents, we will begin with randomized sets of rules and calibrate the model based on empirical data of cellular responses to stress. We will apply a common-garden framework to cultured cells from 16 mammalian species, which will yield genomic data and measures of cell morphology and physiology when exposed to different levels of temperature, glucose, and oxygen. These species include humans, dolphins, bats, and camels, among others, which vary in how they respond to environmental stressors, offering a comparative approach for identifying mechanistic rules whereby cells achieve robustness to environmental stressors. For calibration of the model, we will iteratively select for rules that best lead to the emergent outcomes observed in the cellular assays. Our model is generalized for any species, any cell type, and any environmental stressor, offering many applications of the model beyond our study. This study will increase our understanding of how organisms mitigate environmental stressors at the cellular level such that we can better address how organisms are impacted by and respond to extreme environmental conditions.

This model extends the original Artifical Anasazi (AA) model to include individual agents, who vary in age and sex, and are aggregated into households. This allows more realistic simulations of population dynamics within the Long House Valley of Arizona from AD 800 to 1350 than are possible in the original model. The parts of this model that are directly derived from the AA model are based on Janssen’s 1999 Netlogo implementation of the model; the code for all extensions and adaptations in the model described here (the Artificial Long House Valley (ALHV) model) have been written by the authors. The AA model included only ideal and homogeneous “individuals” who do not participate in the population processes (e.g., birth and death)–these processes were assumed to act on entire households only. The ALHV model incorporates actual individual agents and all demographic processes affect these individuals. Individuals are aggregated into households that participate in annual agricultural and demographic cycles. Thus, the ALHV model is a combination of individual processes (birth and death) and household-level processes (e.g., finding suitable agriculture plots).

As is the case for the AA model, the ALHV model makes use of detailed archaeological and paleoenvironmental data from the Long House Valley and the adjacent areas in Arizona. It also uses the same methods as the original model (from Janssen’s Netlogo implementation) to estimate annual maize productivity of various agricultural zones within the valley. These estimates are used to determine suitable locations for households and farms during each year of the simulation.

This generic individual-based model of a bird colony shows how the influence neighbour’s stress levels synchronize the laying date of neighbours and also of large colonies. The model has been used to demonstrate how this form of simulation model can be recognised as being ‘event-driven’, retaining a history in the patterns produced via simulated events and interactions.

To investigate the potential of using Social Psychology Theory in ABMs of natural resource use and show proof of concept, we present an exemplary agent-based modelling framework that explicitly represents multiple and hierarchical agent self-concepts

The agent-based simulation is set to work on information that is either (a) functional, (b) pseudo-functional, (c) dysfunctional, or (d) irrelevant. The idea is that a judgment on whether information falls into one of the four categories is based on the agent and its network. In other words, it is the agents who interprets a particular information as being (a), (b), (c), or (d). It is a decision based on an exchange with co-workers. This makes the judgment a socially-grounded cognitive exercise. The uFUNK 1.0.2 Model is set on an organization where agent-employee work on agent-tasks.

The Axelrod’s model of cultural dissemination is an agent-model designed to investigate the dissemination of culture among interacting agents on a society.

This version 2.1.0 of the uFunk model is about setting a business strategy (the S in the name) for an organization. A team of managers (or executives) meet and discuss various options on the strategy for the firm. There are three aspects that they have to agree on to set the strategic positioning of the organization.
The discussion is on market, stakeholders, and resources. The team (it could be a business strategy task force) considers various aspects of these three elements. The resources they use to develop the discussion can come from a traditional approach to strategy or from non-traditional means (e.g., so-called serious play, creativity and imagination techniques).
The S-uFunk 2.1.0 Model wants to understand to which extent cognitive means triggered by traditional and non-traditional resources affect the making of the strategy process.

This model is an agent-based simulation written in Python 2.7, which simulates the cost of social care in an ageing UK population. The simulation incorporates processes of population change which affect the demand for and supply of social care, including health status, partnership formation, fertility and mortality. Fertility and mortality rates are drawn from UK population data, then projected forward to 2050 using the methods developed by Lee and Carter 1992.

The model demonstrates that rising life expectancy combined with lower birthrates leads to growing social care costs across the population. More surprisingly, the model shows that the oft-proposed intervention of raising the retirement age has limited utility; some reductions in costs are attained initially, but these reductions taper off beyond age 70. Subsequent work has enhanced and extended this model by adding more detail to agent behaviours and familial relationships.

The version of the model provided here produces outputs in a format compatible with the GEM-SA uncertainty quantification software by Kennedy and O’Hagan. This allows sensitivity analyses to be performed using Gaussian Process Emulation.

AncientS-ABM is an agent-based model for simulating and evaluating the potential social organization of an artificial past society, configured by available archaeological data. Unlike most existing agent-based models used in archaeology, our ABM framework includes completely autonomous, utility-based agents. It also incorporates different social organization paradigms, different decision-making processes, and also different cultivation technologies used in ancient societies. Equipped with such paradigms, the model allows us to explore the transition from a simple to a more complex society by focusing on the historical social dynamics; and to assess the influence of social organization on agents’ population growth, agent community numbers, sizes and distribution.

AncientS-ABM also blends ideas from evolutionary game theory with multi-agent systems’ self-organization. We model the evolution of social behaviours in a population of strategically interacting agents in repeated games where they exchange resources (utility) with others. The results of the games contribute to both the continuous re-organization of the social structure, and the progressive adoption of the most successful agent strategies. Agent population is not fixed, but fluctuates over time, while agents in stage games also receive non-static payoffs, in contrast to most games studied in the literature. To tackle this, we defined a novel formulation of the evolutionary dynamics via assessing agents’ rather than strategies’ fitness.

As a case study, we employ AncientS-ABM to evaluate the impact of the implemented social organization paradigms on an artificial Bronze Age “Minoan” society, located at different geographical parts of the island of Crete, Greece. Model parameter choices are based on archaeological evidence and studies, but are not biased towards any specific assumption. Results over a number of different simulation scenarios demonstrate better sustainability for settlements consisting of and adopting a socio-economic organization model based on self-organization, where a “heterarchical” social structure emerges. Results also demonstrate that successful agent societies adopt an evolutionary approach where cooperation is an emergent strategic behaviour. In simulation scenarios where the natural disaster module was enabled, we observe noticeable changes in the settlements’ distribution, relating to significantly higher migration rates immediately after the modeled Theran eruption. In addition, the initially cooperative behaviour is transformed to a non-cooperative one, thus providing support for archaeological theories suggesting that the volcanic eruption led to a clear breakdown of the Minoan socio-economic system.

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What policy measures are effective in redistributing essential resources during crisis situations such as climate change impacts? We model a collective action institution with different rules for designing and organizing it, and make our analysis specific to various societal contexts.

Our model captures a generic societal context of unequal vulnerability and climate change impact in a stylized form. We represent a community of people who harvest and consume an essential resource to maintain their well-being. However, their ability to harvest the resource is not equal; people are characterized by a ‘resource access’ attribute whose values are uniformly distributed from 0 to 1 in the population. A person’s resource access value determines the amount of resource units they are able to harvest, and therefore the welfare levels they are able to attain. People travel to the centralized resource region and derive well-being or welfare, represented as an energy gain, by harvesting and consuming resource units.

The community is subject to a climate change impact event that occurs with a certain periodicity and over a certain duration. The capacity of resource units to regenerate diminishes during the impact events. Unequal capacities to access the essential resource results in unequal vulnerability among people with regards to their ability to maintain a sufficient welfare level, especially during impact events.

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