Urban greenery such as vertical greenery systems (VGS) can effectively absorb air pollutants emitted by different agents, such as vehicles and manufacturing enterprises. The main challenge is how to protect socially important objects, such as kindergartens, from the influence if air pollution with the minimum of expenditure. There is proposed the hybrid individual- and particle-based model of interactions between vertical greenery systems and air pollutants to identify optimal locations of tree clusters and high-rise buildings where horizontal greenery systems and VGS should be implemented, respectively. The model is implemented in the AnyLogic simulation tool.