EMMIT is an end-user developed agent-based simulation of malaria transmission. The simulation’s development is a case study demonstrating an approach for non-technical investigators to easily develop useful simulations of complex public health problems. We focused on malaria transmission, a major global public health problem, and insecticide resistance (IR), a major problem affecting malaria control. Insecticides are used to reduce transmission of malaria caused by the Plasmodium parasite that is spread by the Anopheles mosquito. However, the emergence and spread of IR in a mosquito population can diminish the insecticide’s effectiveness. IR results from mutations that produce behavioral changes or biochemical changes (such as detoxification enhancement, target site alterations) in the mosquito population that provide resistance to the insecticide. Evolutionary selection for the IR traits reduces the effectiveness of an insecticide favoring the resistant mosquito population. It has been suggested that biopesticides, and specifically those that are Late Life Acting (LLA), could address this problem. LLA insecticides exploit Plasmodium’s approximate 10-day extrinsic incubation period in the mosquito vector, a delay that limits malaria transmission to older infected mosquitoes. Since the proposed LLA insecticide delays mosquito death until after the exposed mosquito has a chance to produce several broods of offspring, reducing the selective pressure for resistance, it delays IR development and gives the insecticide longer effectivity. Such insecticides are designed to slow the evolution of IR thus maintaining their effectiveness for malaria control. For the IR problem, EMMIT shows that an LLA insecticide could work as intended, but its operational characteristics are critical, primarily the mean-time-to-death after exposure and the associated standard deviation. We also demonstrate the simulation’s extensibility to other malaria control measures, including larval source control and policies to mitigate the spread of IR. The simulation was developed using NetLogo as a case study of a simple but useful approach to public health research.

HOW IT WORKS

This model consists of three agents, and each agent type operates per business theories as below.
a. New technologies(Tech): It evolves per sustaining or disruptive technology trajectory with the constraint of project management triangle (Scope, Time, Quality, and Cost).
b. Entrepreneurs(Entre): It builds up the solution by combining Tech components per its own strategy (Exploration, Exploitation, or Ambidex).
c. Consumer(Consumer): It selects the solution per its own preference due to Diffusion of innovation theory (Innovators, Early Adopters, Early Majority, Late Majority, Laggards)
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This model simulates the lithic raw material use and provisioning behavior of a group that inhabits a permanent base camp, and uses stone tools.

A modelling system to simulate Neanderthal demography and distribution in a reconstructed Western Europe for the late Middle Paleolithic.

The Village Project is designed to help archaeologists understand the factors influencing settlement patterns of small-scale agrarian peoples. Although such societies are becoming increasingly rare, they represent the norm throughout most of the Neolithic period the world over.

This models simulates innovation diffusion curves and it tests the effects of the degree and the direction of social influences. This model replicates, extends and departs from classical percolation models.

An individual-based model to evaluate, whether time delays in plant responses to insect herbivory can be beneficial for the plant.

This project is an interactive agent-based model simulating consumption of a shared, renewable resource using a game-theoretic framework with environmental feedback. The primary function of this model was to test how resource-use among AI and human agents degrades the environment, and to explore the socio-environmental feedback loops that lead to complex emergent system dynamics. We implemented a classic game theoretic matrix which decides agents´ strategies, and added a feedback loop which switches between strategies in pristine vs degraded environments. This leads to cooperation in bad environments, and defection in good ones.

Despite this use, it can be applicable for a variety of other scenarios including simulating climate disasters, environmental sensitivity to resource consumption, or influence of environmental degradation to agent behaviour.
The ABM was inspired by the Weitz et. al. (2016, https://pubmed.ncbi.nlm.nih.gov/27830651/) use of environmental feedback in their paper, as well as the Demographic Prisoner’s Dilemma on a Grid model (https://mesa.readthedocs.io/stable/examples/advanced/pd_grid.html#demographic-prisoner-s-dilemma-on-a-grid). The main innovation is the added environmental feedback with local resource replenishment.

Beyond its theoretical insights into coevolutionary dynamics, it serves as a versatile tool with several practical applications. For urban planners and policymakers, the model can function as a ”digital sandbox” for testing the impacts of locating high-consumption industrial agents, such as data centers, in proximity to residential communities. It allows for the exploration of different urban densities, and the evaluation of policy interventions—such as taxes on defection or subsidies for cooperation—by directly modifying the agents’ resource consumptions to observe effects on resource health. Furthermore, the model provides a framework for assessing the resilience of such socio-environmental systems to external shocks.
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The computer model simulates the development of a social network (i.e. formation of friendships and cliques), the (dyadic) interactions between pupils and the development of similarities and differences in their behavioral profiles.

ForagerNet3_Demography is a non-spatial ABM for exploring hunter-gatherer demography. Key methods represent birth, death, and marriage. The dependency ratio is an imporant variable in many economic decisions embedded in the methods.