Identifying how organisms respond to environmental stressors remains of central importance as human impacts continue to shift the environmental conditions for countless species. Some mammals are able to mitigate these environmental stressors at the cellular level, but the mechanisms by which cells are able to do this and how these strategies vary among species is not well understood. At the cellular level, it is difficult to identify the temporal dynamics of the system through empirical data because fine-grained time course samples are both incomplete and limited by available resources. To help identify the mechanisms by which animal cells mitigate extreme environmental conditions, we propose an agent-based model to capture the dynamics of the system. In the model, agents are regulatory elements and genes, and are able to impact the behaviors of each other. Rather than imposing rules for these interactions among agents, we will begin with randomized sets of rules and calibrate the model based on empirical data of cellular responses to stress. We will apply a common-garden framework to cultured cells from 16 mammalian species, which will yield genomic data and measures of cell morphology and physiology when exposed to different levels of temperature, glucose, and oxygen. These species include humans, dolphins, bats, and camels, among others, which vary in how they respond to environmental stressors, offering a comparative approach for identifying mechanistic rules whereby cells achieve robustness to environmental stressors. For calibration of the model, we will iteratively select for rules that best lead to the emergent outcomes observed in the cellular assays. Our model is generalized for any species, any cell type, and any environmental stressor, offering many applications of the model beyond our study. This study will increase our understanding of how organisms mitigate environmental stressors at the cellular level such that we can better address how organisms are impacted by and respond to extreme environmental conditions.

The Rigor and Transparency Reporting Standard (RAT-RS) is a tool to improve the documentation of data use in Agent-Based Modelling. Following the development of reporting standards for models themselves, attention to empirical models has now reached a stage where these standards need to take equally effective account of data use (which until now has tended to be an afterthought to model description). It is particularly important that a standard should allow the reporting of the different uses to which data may be put (specification, calibration and validation), but also that it should be compatible with the integration of different kinds of data (for example statistical, qualitative, ethnographic and experimental) sometimes known as mixed methods research.

For the full details on the RAT-RS, please refer to the related publication “RAT-RS: A Reporting Standard for Improving the Documentation of Data Use in Agent-Based Modelling” (http://dx.doi.org/10.1080/13645579.2022.2049511).

Here we provide supplementary material for this article, consisting of a RAT-RS user guide and RAT-RS templates.

（An empty output folder named “NETLOGOexperiment” in the same location with the LAKEOBS_MIX.nlogo file is required before the model can be run properly）
The model is motivated by regime shifts (i.e. abrupt and persistent transition) revealed in the previous paleoecological study of Taibai Lake. The aim of this model is to improve a general understanding of the mechanism of emergent nonlinear shifts in complex systems. Prelimnary calibration and validation is done against survey data in MLYB lakes. Dynamic population changes of function groups can be simulated and observed on the Netlogo interface.
Main functional groups in lake ecosystems were modelled as super-individuals in a space where they interact with each other. They are phytoplankton, zooplankton, submerged macrophyte, planktivorous fish, herbivorous fish and piscivorous fish. The relationships between these functional groups include predation (e.g. zooplankton-phytoplankton), competition (phytoplankton-macrophyte) and protection (macrophyte-zooplankton). Each individual has properties in size, mass, energy, and age as physiological variables and reproduce or die according to predefined criteria. A system dynamic model was integrated to simulate external drivers.
Set biological and environmental parameters using the green sliders first. If the data of simulation are to be logged, set “Logdata” as true and input the name of the file you want the spreadsheet(.csv) to be called. You will need create an empty folder called “NETLOGOexperiment” in the same level and location with the LAKEOBS_MIX.nlogo file. Press “setup” to initialise the system and “go” to start life cycles.

Substitution of food products will be key to realising widespread adoption of sustainable diets. We present an agent-based model of decision-making and influences on food choice, and apply it to historically observed trends of British whole and skimmed (including semi) milk consumption from 1974 to 2005. We aim to give a plausible representation of milk choice substitution, and test different mechanisms of choice consideration. Agents are consumers that perceive information regarding the two milk choices, and hold values that inform their position on the health and environmental impact of those choices. Habit, social influence and post-decision evaluation are modelled. Representative survey data on human values and long-running public concerns empirically inform the model. An experiment was run to compare two model variants by how they perform in reproducing these trends. This was measured by recording mean weekly milk consumption per person. The variants differed in how agents became disposed to consider alternative milk choices. One followed a threshold approach, the other was probability based. All other model aspects remained unchanged. An optimisation exercise via an evolutionary algorithm was used to calibrate the model variants independently to observed data. Following calibration, uncertainty and global variance-based temporal sensitivity analysis were conducted. Both model variants were able to reproduce the general pattern of historical milk consumption, however, the probability-based approach gave a closer fit to the observed data, but over a wider range of uncertainty. This responds to, and further highlights, the need for research that looks at, and compares, different models of human decision-making in agent-based and simulation models. This study is the first to present an agent-based modelling of food choice substitution in the context of British milk consumption. It can serve as a valuable pre-curser to the modelling of dietary shift and sustainable product substitution to plant-based alternatives in Britain.

The study goes back to a model created in the 1990s which successfully tried to replicate the changes of the percentages of female teachers among the teaching staff in high schools (“Gymnasien”) in the German federal state of Rheinland-Pfalz. The current version allows for additional validation and calibration of the model and is accompanied with the empirical data against which the model is tested and with an analysis program especially designed to perform the analyses in the most recent journal article.

This repository contains: (1) a model calibration procedure that identifies a set of diverse, plausible models; and (2) an ABM of smallholder agriculture, which is used as a case study application for the calibration method. By identifying a set of diverse models, the calibration method attends to the issue of “equifinality” prevalent in complex systems, which is a situation where multiple plausible process descriptions exist for a single outcome.

The NIER model is intended to add qualitative variables of building owner types and peer group scales to existing energy efficiency retrofit adoption models. The model was developed through a combined methodology with qualitative research, which included interviews with key stakeholders in Cleveland, Ohio and Detroit and Grand Rapids, Michigan. The concepts that the NIER model adds to traditional economic feasibility studies of energy retrofit decision-making are differences in building owner types (reflecting strategies for managing buildings) and peer group scale (neighborhoods of various sizes and large-scale Districts). Insights from the NIER model include: large peer group comparisons can quickly raise the average energy efficiency values of Leader and Conformist building owner types, but leave Stigma-avoider owner types as unmotivated to retrofit; policy interventions such as upgrading buildings to energy-related codes at the point of sale can motivate retrofits among the lowest efficient buildings, which are predominantly represented by the Stigma-avoider type of owner; small neighborhood peer groups can successfully amplify normal retrofit incentives.

The model answers the question how homophily and number of close-links in small-world network influences behavior of consumats. The results show that the more close-links the more probable the consumat follows the major behavior, but homophilly blocks the major behavior and supports survival of the minor behavior.

This is an initial exploratory exercise done for the class @ http://thiagomarzagao.com/teaching/ipea/ Text available here: https://arxiv.org/abs/1712.04429v1
The program:
Reads output from an ABM model and its parameters’ configuration
Creates a socioeconomic optimal output based on two ABM results of the modelers choice
Organizes the data as X and Y matrices
Trains some Machine Learning algorithms
…

The model includes different formulations how agents make decisions in irrigation games and this is compared with empirical data. The aim is to test different theoretical models, especially explaining effect of communication.